AGenDA: gene prediction by cross-species sequence comparison
نویسندگان
چکیده
منابع مشابه
AGenDA: gene prediction by cross-species sequence comparison
Automatic gene prediction is one of the major challenges in computational sequence analysis. Traditional approaches to gene finding rely on statistical models derived from previously known genes. By contrast, a new class of comparative methods relies on comparing genomic sequences from evolutionary related organisms to each other. These methods are based on the concept of phylogenetic footprint...
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All three approaches share a number of common properties, which we list before going on to explore their differences: • Most algorithms locate protein-coding regions as opposed to whole genes. Nevertheless “gene prediction” remains standard nomenclature. • There is a significant amount of application-specific knowledge going into these designs. Of the systems referenced here only VEIL comes clo...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2004
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkh386